hif 2α in 1 — TargetMol Chemicals

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Search Results for " hif 2α in 1 "

Compounds

Cat No.	Product Name	Targets
T15482	HIF-2α-IN-1	HIF
	HIF-2α-IN-1 is a potent HIF-2α inhibitor with IC50 values less than 500 nM.	HIF
T61102	HIF-1/2α-IN-2
	HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α. This compound elicits an iron starvation response by specifically targeting ISCA2, a key protein involved in Iron Sulfur ...
T61442	HIF-1/2α-IN-1
	HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α. Its inhibitory effect on HIF-2α activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/2α-IN-1 has the ability to decrea...
T61367	HIF-2α-IN-6
	HIF-2α-IN-6 (117) is a HIF-2α inhibitor [1].
T61614	HIF-2α-IN-5
	HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].
T72997	HIF-2α-IN-7
	HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC 50 value of 6 nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer , liver ...
T78937	HIF-2α-IN-9	HIF/HIF Prolyl-Hydroxylase
	HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes within tumor cells while reactivating macrophage-mediated tumor immun...	HIF/HIF Prolyl-Hydroxylase
TP2046	TAT-cyclo-CLLFVY
	Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expressi...
T36492	CMC2.24
	CMC2.24 (TRB-N0224) is an orally active tricarbonylmethane agent that demonstrates effectiveness in inhibiting Ras activation and the downstream effector ERK1/2 pathway, thus effectively combating pancreatic tumor format...